Arcade Stick
Joysticks have been around since the advent of gaming, so the learning curve should not be steep, and joysticks should connect quite well with your brain. There are many customization options from joysticks to buttons.
There is a decent selection of brands that offer different arcade sticks for different tastes. However, packing an arcade stick in a suitcase can prove to be a challenge due to the joystick sticking out, meaning that breaking is possible. That is unless your arcade stick has a detachable joystick design.
Hitbox
With the hitbox, you can do 360 motions quicker. In addition, you should never miss pressing forward, back, up, or down perfectly as the range of motion present with joysticks does not apply. You move from direction to direction at breakneck speed.
Setting both hands on a hitbox is comfortable due to the balance created by not having to place your hands in different positions (as a joystick would have to tilt one hand up while the other hand faces down).
Mixbox
Many of the benefits of the hitbox also apply to the mixbox. You can enjoy the proximity of the directional keys to perform a variety of actions.
On the other hand, you might feel that the clustered keys do not provide ample leeway for flexible movement. Furthermore, you cannot comfortably rest your fingers on all directional keys at the same time.
Needless to say, the mixbox is a reasonable transition for PC players who are used to keyboards but would like to step up their game.